Module Title:   Genomic Coding

Module Credit:   10

Module Code:   ENG4094M

Academic Year:   2015/6

Teaching Period:   Semester 1

Module Occurrence:   A

Module Level:   FHEQ Level 7

Module Type:   Standard module

Provider:   Engineering

Related Department/Subject Area:   School of Engineering NOT IN USE - replaced by EX 2014

Principal Co-ordinator:   Professor SJ Shepherd

Additional Tutor(s):   -

Prerequisite(s):   None

Corequisite(s):   None

Aims:
To engender specialist knowledge and understanding of the principles of bioinformatics and how information technology can be applied to problems in computational biology and clinical medicine. To develop mathematical skills in relation to bioinformatics and an understanding of the role of information technology in the gemonic revolution

Learning Teaching & Assessment Strategy:
The factual basis, concepts and principles of the subject will be introduced through lectures in which routine analysis will be demonstrated. The material is reinforced through whole-group seminars. Tutorial exercises, recommended texts and lecture notes provided enable students to consolidate what they have learned. In the remaining time, students have the opportunity to reflect on, explore and extend their knowledge and understanding and to prepare for the formal written examination that assesses their knowledge and understanding of the subject.

Lectures:   16.00          Directed Study:   76.00           
Seminars/Tutorials:   8.00          Other:   0.00           
Laboratory/Practical:   0.00          Formal Exams:   0.00          Total:   100.00

On successful completion of this module you will be able to...

Understand the nature of the information contained within genomic code; Locate and analyse bioinformatics data published on the internet; Describe the principles and techniques underlying the analysis; Critically evaluate and analyse genomic data for medical use; Critically evaluate the performance of different bioinformatic techniques.

On successful completion of this module you will be able to...

use a range of bioinformatic techniques to analyse genomic data; write simple programs in a computer language of their choice to manipulate biological information into different forms for various uses.

On successful completion of this module you will be able to...

Solve problems systematically.

  Coursework   100%
 
  Report

Outline Syllabus:
* What is bioinformatics? The role of information technology in biology and medicine.
* Elementary information theory. Elementary coding theory. Nature of information. Information encoding, storage and transmission. Error-correcting codes.
* Elementary statistics. Expected distributions. Genomic alphabet. Proteomic alphabet. Genomic information coding. Sequence analysis. Sequence alignment. Pattern matching. Pattern discovery. Applications to taxonomy and phylogeny. Motif discovery. Codons, scriptons, cistrons and replicons. Regulatory sequences. Spectral analysis and the periodogram. Automated discovery of ORFs.

Version No:  2